The Southampton neighborhood occupies a one square mile area in the southwest corner of the City of Saint Louis (Missouri). The perimeter streets of Chippewa, Hampton, Eichelberger and Kingshighway are mixed commercial and residential, with Macklind, a small but vibrant commercial center bisecting the neighborhood.  The eclectic and charming structures are occupied by friendly neighbors, welcoming businesses, and an active all-volunteer neighborhood association.  From our family to yours, we invite you to come explore all Southampton has to offer!   Join Us